FootXtra – Football News & Updates FootXtra brings you the latest football news, live updates, match previews, transfer stories, and in-depth analysis from leagues and tournaments around the world. Stay connected to the beautiful game every day.
AC Milan give Ardon Jashari his first start with Ruben Loftus-Cheek and Rafael Leao in the Coppa Italia Round of 16, where Lazio have Taty Castellanos back with Mattia Zaccagni.
It kicks off at the Stadio Olimpico in Rome at 20.00 GMT.
You can follow all the build-up and action as it happens on the Liveblog.
The winners of this tie will go on to face either Bologna or Parma in the quarter-final.
As there is no extra time at this stage of the tournament, if the teams are level after 90 minutes, they go straight to a penalty shoot-out.
This match arrives just days after a controversial and heated encounter at San Siro in Serie A, where Milan won 1-0 amid tension over a late VAR call regarding a Lazio penalty appeal.
That result put the Rossoneri joint top of the table, but their Coppa Italia adventure started early this season with wins over Bari and Lecce.
Youssouf Fofana, Santiago Gimenez and Zachary Athekame haven’t made the trip, while Christian Pulisic is on the bench after a muscular issue.
The big news is that summer signing Jashari finally gets his first start after fracturing his fibula in August.
Samuele Ricci, Koni De Winter and Pervis Estupinan also step into the starting XI, while Loftus-Cheek is given a more advanced role as support to Leao.
The Portuguese forward has a particular fondness for facing Lazio, as he scored four and provided five assists against them in 13 competitive games.
Lazio are still fuming after that late VAR call at San Siro on Sunday and have the usual injury problems, missing Danilo Cataldi, Nicolò Rovella and Samuel Gigot, while Elseid Hysaj was cut from the squad list.
Matteo Cancellieri is back in the group after injury and Castellanos returns for his first start since October 4.
Matias Vecino pulls the midfield strings with Matteo Guendouzi and Toma Basic.
Lazio: Mandas; Marusic, Gila, Romagnoli, Pellegrini; Guendouzi, Vecino, Basic; Isaksen, Castellanos, Zaccagni
Milan: Maignan; Tomori, De Winter, Pavlovic; Saelemaekers, Ricci, Jashari, Rabiot, Estupinan; Loftus-Cheek; Leao
FIFA World Cup
