Serie A official Week 22 line-ups: Roma vs. Milan

Donyell Malen, Paulo Dybala and Matias Soulé lead the Roma attack, while Milan turn to Rafael Leao, Luka Modric and Christopher Nkunku.

It kicks off at the Stadio Olimpico in Rome at 19.45 GMT (20.45 CET).

You can follow all the build-up and action as it happens from today’s Serie A games on the Liveblog.

This is a massive clash between second and fourth, so has importance both for the Scudetto race and those precious Champions League spots.

Roma won three Serie A games in a row and are fresh from Thursday’s 2-0 Europa League victory over VfB Stuttgart.

Malen scored on his debut in the 2-0 win against Torino, but was cup-tied midweek, so returns to the starting XI here with support from both Dybala and Soulé.

The problems are in defence, where Mario Hermoso will be out for a month with a muscular lesion, joining Devyne Rensch, Artem Dovbyk and Angelino on the treatment table, so Daniele Ghilardi plays.

Stephan El Shaarawy and Neil El Aynaoui return to the bench, along with new signing Robinio Vaz.

Milan are unbeaten since the opening weekend in Serie A, but while they have generally done well in the big games, it’s against the smaller clubs that they’ve stuttered.

Santiago Gimenez is the only injury case, as Alexis Saelemaekers shook off a knock to start against the club where he was on loan last season.

Strahinja Pavlovic is still not at 100 per cent after needing nine stitches for a cut to his head, so Koni De Winter keeps his spot in defence.

The big news is Christian Pulisic dropping to the bench, so Leao is partnered by Nkunku, with Modric returning to the midfield alongside Adrien Rabiot and Samuele Ricci.

Roma: Svilar; Mancini, Ndicka, Ghilardi; Celik, Koné, Cristante, Wesley; Dybala, Soulé; Malen

Milan: Maignan; Tomori, Gabbia, De Winter; Saelemaekers, Ricci, Modric, Rabiot, Bartesaghi; Nkunku, Leao