
Inter are forced into changes in defence and midfield, while Francesco Pio Esposito partners Lautaro Martinez for the trip to Daniele De Rossi’s revitalised Genoa.
It kicks off at the Stadio Luigi Ferraris, also known as Marassi, at 17.00 GMT.
You can follow all the build-up and action as it happens from today’s five Serie A games on the Liveblog.
This has been a difficult few days for Cristian Chivu, as just after an exhilarating 4-0 victory over Como, he had to deal with a second consecutive Champions League defeat, this one to a ridiculously soft Liverpool penalty.
To make matters worse, Hakan Calhanoglu and Francesco Acerbi both limped off during that game and are out of action, along with Denzel Dumfries, Matteo Darmian, Tomas Palacios and Raffaele Di Gennaro.
Changes are therefore forced, including Carlos Augusto stepping in on the left, with Piotr Zielinski and Petar Sucic in midfield.
Francesco Pio Esposito is chosen to partner Lautaro Martinez upfront.
Genoa have been revitalised since Daniele De Rossi replaced Patrick Vieira, earning two draws and back-to-back victories over Verona and Udinese to break out of the relegation zone.
Leo Ostigard, Junior Messias, Hugo Cuenca, Maxwel Cornet and Benjamin Siegrist are still out of action, but Morten Frendrup returns to midfield.
Brooke Norton-Cuffy scored last week and bolstered his transfer value, while Vitinha supports Lorenzo Colombo upfront, leaving Inter-owned Valentin Carboni on the bench.
Genoa: Leali; Marcandalli, Otoa, Vasquez; Norton-Cuffy, Frendrup, Malinovskyi, Ellertsson, Martin; Vitinha, Colombo
Inter: Sommer; Bisseck, Akanji, Bastoni; Luis Henrique, Barella, Zielinski, Sucic, Carlos Augusto; Lautaro Martinez, Pio Esposito
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