
Inter look to Francesco Pio Esposito, Andy Diouf and Luis Henrique in their Coppa Italia Round of 16 tie against Venezia, the only Serie B side still in the competition.
It kicks off at San Siro at 20.00 GMT.
You can follow all the build-up and action as it happens from this game and Napoli vs. Cagliari on the Liveblog.
The winners of this fixture will go on to face either Roma or Torino in the quarter-finals.
There is no extra time in the Coppa Italia until the semi-final stage, so if the tie is all square after 90 minutes, it goes straight to a penalty shoot-out.
Inter are one point off joint leaders Napoli and AC Milan in Serie A, so are inevitably rotating the squad ahead of Saturday’s showdown with high-flying Como.
Some choices are forced upon Cristian Chivu, as Denzel Dumfries, Ange-Yoan Bonny, Raffaele Di Gennaro and Tomas Palacios are still out of action.
Josep Martinez returns in goal for the first time since he was involved in a fatal car accident in late October.
There are rare chances to start for Luis Henrique, Andy Diouf and Davide Frattesi, supporting centre-forward Pio Esposito.
Venezia are the only remaining Serie B side still in the Coppa Italia last 16, having eliminated Mantova and Hellas Verona in the tournament so far.
Following a rough start to the Serie B campaign, they have picked up with three consecutive victories.
Coach Giovanni Stroppa also rotates his side, leaving out Inter-owned goalkeeper Filip Stankovic, with Alessandro Plizzari injured.
Alfred Duncan faces his former club, along with former Inter youth academy product Andrea Adorante on the bench.
Inter: J Martinez; Bisseck, De Vrij, Carlos Augusto; Diouf, Frattesi, Zielinski, Sucic, Luis Henrique; Thuram, Esposito
Venezia: Grandi; Korac, Venturi, Sidibe; Sagrado, Lella, Bohinen, Duncan, Haps; Compagnon, Casas
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