After disappointing defeats against rivals Manchester City and Bayern Munich respectively it’s a chance for Manchester United and Chelsea to pick themselves up in the Premier League.
United have just four points from four Premier League games so far and need a win in front of their own fans.
Chelsea have won twice and are unbeaten in the Premier League so far.
United centre-back Lisandro Martinez remains sidelined with a long-term knee injury but full-back Diogo Dalot could return after being out since withdrawing from Portugal’s squad earlier this month with a muscle injury.
Forward Matheus Cunha and midfielder Mason Mount could return, having missed the defeat at City with injuries suffered during the 3-2 home win over Burnley on August 30.
With goalkeeper Andre Onana now on loan to Turkish side Trabzonspor, manager Ruben Amorim chose Turkiye international Altay Bayindir rather than new signing Senne Lammens – a decision the Portuguese could reconsider after another poor defensive display.
Captain Bruno Fernandes could become the 28th United player to reach 200 Premier League appearances, with only David Beckham (62) eclipsing the Portugal international’s total of 51 assists across that many games.